Since the legalization of hemp, its cultivation, production, and distribution, CBD (cannabidiol), one of the main chemical compounds (cannabinoids) in the plant species, has been rapidly thriving in the market and is now becoming well-known. But, we know about CBD and THC (tetrahydrocannabinol), the prominent psychoactive component in marijuana. What about the other cannabinoids found in the hemp plant?
Scientists believe there could be over 100 cannabinoids to be found in the species of cannabaceae ‒ of which both hemp and marijuana are derived from. These chemicals are unique to the species and have the unique ability to interact with the human body’s natural cannabinoid receptors.
Below, we’ll take a closer look at a few of the other major cannabinoids researchers have found in hemp so far and their potential uses.
A lesser-known and less studied cannabinoid than THC and CBD, CBC shows great potential in helping with numerous conditions such as chronic pain. Studies on the chemical’s effect on the human body focus on its ability to block the perception of pain. Recent studies discovered that CBC combined with CBD decreased pain signals in mice and the combination of CBC and THC also had a powerful anti-inflammatory effect on mice.
Other purported benefits include alleviating cancer and tumor growth, acne treatment, healthy brain function, and antidepressant properties.
Although produced from heated or oxidized THC, CBN hasn’t been shown to be psychoactive in lab studies. Producing CBN-rich plants means exposing them to oxygen for long periods of time which made CBN undesirable among farmers, retailers, and consumers.
Its benefits include bone tissue growth, anti-inflammatory and pain relief properties. It is said to be a possible sedative, sleep aid, appetite stimulant, and anti-convulsive agent. CBN seems to work best synergistically with CBD and THC.
Because of its low content in most strains (usually <1%), CBG is considered a minor cannabinoid but is arguably one of the most important in the cannabis plant. The raw cannabis plant produces cannabinoids in a non-active acidic state. They first have to undergo a decarboxylation process, in which acidic compounds are exposed to high temperatures or UV lights, then transform into their non-acidic active forms. Cannabigerolic acid (CBGA) is the originator of some of the major cannabinoids ‒ tetrahydrocannabinolic acid (THCA) and cannabidiolic acid (CBDA) which then convert to THC and CBD respectfully. It has also shown to produce the precursor to the soothing cannabinoid CBC.
CBG’s potential medical benefits include the possibility of treating glaucoma, inflammatory bowel disease (in animal experiments using mice), protecting neurons against Huntington’s disease (in mice), fighting cancer, inhibiting the growth of colorectal cancer cells, according to evidence from research, an effective antibacterial agent, possible appetite stimulant for persons suffering from cachexia and prevention of bladder dysfunction disorders.
THCV compound makeup is quite similar to THC’s, but it affects the body differently. It is capable of behaving much like THC if taken in high doses giving the user a “high”.
THCV may positively impact bone cell growth, encourage weight loss, and improve insulin resistance. Although more research is needed, the chemical compound has the potential to treat conditions like anxiety, tremors, and inflammation.
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